What causes a stent to fail?

What causes a stent to fail?

The two major causes of stent failure are stent thrombosis (ST) and in-stent restenosis (ISR).

What causes a stent to narrow?

Restenosis happens because the elastic artery walls tend to slowly move back in after being stretched open. Also, the artery narrows if tissue growth during healing is excessive. Bare metal stents (BMS) were developed to help resist the reopened artery’s tendency to close while healing.2019-01-22

How do they fix a collapsed stent?

The most common method is to maneuver a drug-coated stent wrapped around a balloon into the middle of the closed-up stent. Inflating the balloon pushes aside the material obstructing the old stent and opens the new one.

When does in-stent restenosis occur?

Restenosis generally occurs within 3 to 6 months after your stent is placed.2021-06-13

What are the symptoms of a collapsed stent?

Symptoms will usually tell you if there’s a problem. If that happens, you usually have symptoms—like chest pain, fatigue, or shortness of breath. If you do have symptoms, a stress test can help your doctor see what’s going on. It can show if a blockage has returned or if there’s a new blockage.

How common is in stent restenosis?

Ellis says, “in-stent restenosis still occurs in approximately 3 to 10% of patients within six to nine months, and sometimes afterwards. We have learned that restenosis is a very complex process.” Some known causes include: Stents that are too small or misaligned in the blood vessel.2019-12-03

How is stent stenosis treated?

The currently available options for treatment of ISR include angioplasty alone, repeat stenting with DES or drug-coated balloons.

How often do heart stents collapse?

In the majority of patients (118; 78.1%), stenting was performed as provisional; in the remaining 33 (21.8%) as a bailout procedure. A total of 175 (3.3%) stents in 151 (4.3%) patients failed.

Is narrowing of the arteries serious?

Atherosclerosis is a potentially serious condition where arteries become clogged with fatty substances called plaques, or atheroma.

How does a stent become dislodged?

Stent dislodgement can occur due to arterial tortuosity and calcification, direct stenting, or the inadequate coaxiality of the guide catheter; therefore, adequate predilation may help to prevent stent dislodgement.

Which medication coating on the stent would reduce restenosis?

Importantly, even when it is used locally with drug-eluting stents (DESs), sirolimus appears to be the most effective drug to prevent restenosis after PCI.2005-11-01

Can a fall dislodge a stent?

Because the stent is embedded in the artery wall, it will remain in place even during any severe jolts.

How common is stent collapse?

A total of 175 (3.3%) stents in 151 (4.3%) patients failed. Failure to deliver the stent to the lesion site was the main cause in 139 patients (92%) and failure either to expand adequately the stent or premature disengagement of the stent from the balloon in only 12 patients (8%).

How often does stent restenosis occur?

Despite advances, Dr. Ellis says, “in-stent restenosis still occurs in approximately 3 to 10% of patients within six to nine months, and sometimes afterwards. We have learned that restenosis is a very complex process.”2019-12-03

How can stent restenosis be prevented?

Prevention of in-stent restenosis These strategies are 1) mechanical strategies, 2) systemic drugs, 3) intracoronary radiation, 4) drug-coated and eluting stents, and 5) prospective therapies.

Is it common for stents to collapse?

Immediate collapse of implanted coronary stent is a rare complication, and, to our knowledge, few authors have reported it previously.2017-07-17

What causes narrowing of the heart artery?

Plaque is made up of cholesterol deposits. Plaque buildup causes the inside of the arteries to narrow over time. This process is called atherosclerosis. Coronary artery disease is caused by plaque buildup in the wall of the arteries that supply blood to the heart (called coronary arteries).2021-07-19

CAD: In-Stent Restenosis – Cleveland Clinic

CAD: In-Stent Restenosis Appointments 800.659.7822 Appointments & Locations Talk to a Heart Nurse Contact Us Management and Treatment Outlook / Prognosis Living With Resources Overview What is Restenosis? Restenosis means that a section of blocked artery that was opened up with angioplasty or a stent has become narrowed again.

In-stent Restenosis

In-stent restenosis (ISR) is the narrowing of a stented coronary artery lesion. The mean time from percutaneous coronary intervention (PCI) to ISR was 12 months with drug-eluting stents (DES) and 6 months with bare metal stents (BMS). ISR typically presents as recurrent angina.

Restenosis: Definition, Symptoms, In-Stent Thrombosis, and

In-stent restenosis (ISR) Angioplasty, a type of percutaneous coronary intervention (PCI), is a procedure used to open up blocked arteries. During the procedure, a small metal scaffold, called a

In-Stent Restenosis: Pathophysiology and Treatment

Management of in-stent restenosis (ISR) remains a clinical challenge after both bare metal stent and drug-eluting stent placement. Autopsy studies and intravascular imaging have augmented our understanding of the pathophysiology of ISR. The clinical presentation and symptoms vary considerably among …

Understanding and managing in-stent restenosis: a review

In-stent restenosis (ISR) has always been considered the “enemy” for the interventional cardiologists, thus many technical improvements in the last 20 years aimed at reducing its occurrence: firstly, newer generation bare metal stents (BMS) ( 3 ), then drug-eluting stents (DES) ( 4) and finally drug-coated balloons (DCB) ( 5, 6 ).

Restenosis – StatPearls – NCBI Bookshelf

In-segment restenosis is often defined as restenosis anywhere between 5 mm from the proximal and distal edges of the stent.[1] Recurrent in-stent restenosis is defined as the failure of at least two revascularization procedures at the stent segment.[2] Restenosis is the reduction in the diameter of the vessel lumen after angioplasty.

Why Does Restenosis Happen? – Cleveland Clinic

Despite advances, Dr. Ellis says, “in-stent restenosis still occurs in approximately 3 to 10% of patients within six to nine months, and sometimes afterwards. We have learned that restenosis is a very complex process.” Some known causes include: • Stents that are too small or misaligned in the blood vessel. • Older-generation stents.

Restenosis, in-stent restenosis causes, symptoms

Angiographically, in-stent restenosis is more than 50% stenosis within or immediately adjacent to a previously stented region. Clinical restenosis occurs when there is a recurrence of clinical manifestations of ischemia in the setting of in-stent restenosis, often requiring a repeat revascularization procedure.

Restenosis – Wikipedia

When a stent is used and restenosis occurs, this is called in-stent restenosis or ISR. If it occurs following balloon angioplasty, this is called post-angioplasty restenosis or PARS. The diagnostic threshold for restenosis in both ISR or PARS is ≥50% stenosis.

In-stent restenosis of the SFA | Gore Medical Latin America

Consider the complexity and therapeutic challenge of in-stent restenosis (ISR) in the superficial femoral artery (SFA) ISR is the “Achilles’ heel” of peripheral vascular interventions1 Reported to occur within a year in up to 45% of femoropopliteal lesions treated with bare metal stents2-4 Lesion length is a risk factor for ISR for bare metal and drug-eluting stents5-6 There are a limited

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Tips and Tricks for Management of In-Stent Restenosis | SCAI

In-stent restenosis (ISR), defined as >50 percent diameter stenosis, accounts for about 10 percent of all percutaneous coronary interventions (PCIs) according to the National Cardiovascular Data Registry (NCDR). 1 While rates of ISR have declined with the use of drug-eluting stents (DESs), the optimal treatment for DES-ISR remains unknown.

In-Stent Restenosis – an overview | ScienceDirect Topics

In-stent restenosis (ISR) is primarily due to neointimal hyperplasia produced by vessel injury of the balloon and/or stent struts. The injured segments promote activation of platelets, mural thrombus, and inflammatory cells. Vascular injury, mural thrombus, and a metallic foreign body activate circulating neutrophils and tissue macrophages.

Restenosis – an overview | ScienceDirect Topics

Restenosis is the re-narrowing of the vessel after treatment by balloon and stent leading to recurrence of anginal symptoms. Restenosis is not considered a true complication but is an adverse event requiring retreatment or CABG. Restenosis is caused mostly by intimal hyperplasia and rarely by vessel recoil after stenting.

In-Stent Restenosis? | Circulation: Cardiovascular

Soon after, it was apparent that these stents led to a troubling phenomenon of in-stent restenosis (ISR), which requires repeat revascularization, was associated with increased morbidity and mortality, and posed a therapeutic challenge.

Restenosis of Drug-Eluting Stents | Circulation

high rates of in-stent restenosis (isr) associated with bare-metal stents (bmss) led to the development of drug-eluting stents (dess), which modified the healing process after stent implantation, attenuating neointimal formation, and resulting in a reduction of the incidence of isr to rates ranging from 5% to 10%. 1 despite improvements in stent …

In-Stent Restenosis – Boston Scientific

Medical Specialties > Interventional Cardiology > In-Stent Restenosis In-Stent Restenosis. Restenosis and In-stent restenosis (ISR) have been the “enemy” for interventional cardiologists for the past 40 years and many of the technical improvements in the last 20 years were aimed at reducing its occurrence: firstly, with newer generation bare metal stents, and then drug-eluting stents and

In-Stent Restenosis – Thoracic Key

in order to quantitatively evaluate the magnitude of isr, 2 parameters have to be taken into account: (1) binary angiographic restenosis, defined as a luminal narrowing of 50% or more measured by follow-up coronary angiography 6 and (2) late lumen loss (lll), defined as the difference in millimeters between the diameter of a stented segment …

Coronary in-stent restenosis | Radiology Reference Article

Coronary in-stent restenosis usually occurs as a result of a reaction to arterial wall injury and can be focal or diffuse. It is considered as a distinct pathophysiological process with the following contributing factors 1-4: prolapse of the disrupted plaque. elastic recoil of the arterial wall. constrictive negative remodeling.

In-stent restenosis | definition of in-stent restenosis by

In-stent restenosis | definition of in-stent restenosis by Medical dictionary in-stent restenosis in-stent restenosis Interventional cardiology Scar-induced reclosure of a previously stenosed coronary artery, a complication seen in ±20% of Pts undergoing stent placement for CAD. See Coronary artery disease, Stent. Cf Late stent thrombosis.

Treatment of In-stent Restenosis – Past, Present and

Scale of the Problem Treatment of patients with in-stent restenosis (ISR) remains a significant clinical problem.1 Bare-metal stents (BMS) continue to be used in a large number of patients undergoing percutaneous coronary interventions (PCIs).1-4 BMS are indicated in patients with high bleeding risks or those who are unable to maintain long-term dual antiplatelet therapy.


Restenosis is a gradual re-narrowing of the stented segment that occurs mostly between 3 to 12 months after stent placement. It usually presents as recurrent angina, but can present as acute myocardial infarction in approximately 10 percent of patients. It can usually be managed by repeat percutaneous revascularization.

In‐Stent Restenosis – Kim – 2011 – Cardiovascular

Nevertheless, despite advances in stent and delivery system design, procedural technique, and pharmacologic therapy, the overall rate of restenosis within implanted BMS (i.e., in-stent restenosis [ISR]) remains tangible— approximately 20% overall with reported rates of greater than 40% in certain, high-risk patient subsets [2-4].

In-stent Stenosis: Pathology and Implications for The

Patients with in-stent restenosis treated with brachytherapy have lower target vessel revascularisation rates, lower binary restenosis rates, and larger MLDs than control vessels, up to three years after the procedure (summarised in table 2). The effects of brachytherapy are evident at six months, but persist to three years.

In-Stent Restenosis Accounts for 10% of All PCIs, National

Although in-stent restenosis (ISR) is not on the radar of operators as much as it once was, the proportion of PCIs performed for it has remained steady over time in the United States, accounting for one in 10 interventions, according to an analysis of patients treated from 2009 to 2017.

In stent restenosis – SlideShare

cutting or scoring balloons • The use of before DES or DCB is potentially valuable, and this approach is being assessed in ongoing randomized trials (e.g., ISAR- DESIRE 4 [Intracoronary Stenting and Angiographic Results: Optimizing Treatment of Drug Eluting Stent In-Stent Restenosis 10. “Onion-skin” phenomena Stent in stent 11.

IN STENT RESTENOSIS – slideshare.net

INCIDENCE In general, rates of ISR range from 3% to 20% with drug- eluting stents and 16% and 44% with BMS. This occurs mostly between 3 to 20 mo after stent placement Beyond 1 year, rate of BMS restenosis is negligible and most stenting events are related to disease progression in vessel segments other than the stented lesion.

DCB vs. DES for Treatment of In-Stent Restenosis

What is the role of drug-coated balloon (DCB) angioplasty in the treatment of coronary in-stent restenosis (ISR)? Methods: Patient-level data from 10 randomized trials comparing DCB angioplasty to repeat drug-eluting stent (DES) implantation in the treatment of coronary ISR (710 patients with BMS [bare-metal stent]-ISR and 1,248 with DES-ISR

REWARDS- In-stent Restenosis – Full Text View

In-Stent Coronary Artery Restenosis. Detailed Description: Drug-eluting coronary stents (DES) significantly reduced the rate of neointimal hyperplasia and in-stent restenosis (ISR) compared to bare metal stents (BMS) for the treatment of coronary artery disease. In addition, the continued evolution in scaffold and polymer design with

In-Stent Restenosis | Interventional Cardiology, 2e

The safety and efficacy of percutaneous coronary interventions (PCI) have been drastically improved by the introduction of bare metal stent (BMSs) in clinical practice. 1 However, a new pathologic entity arose with the implantation of BMSs within coronary arteries: in-stent restenosis (ISR). 2 ISR can be defined as the in-stent lumen narrowing that pathobiologically relates to the phenomenon

Coronary in-stent restenosis | Radiology Reference Article

Coronary in-stent restenosis usually occurs as a result of a reaction to arterial wall injury and can be focal or diffuse. It is considered as a distinct pathophysiological process with the following contributing factors 1-4: prolapse of the disrupted plaque. elastic recoil of the arterial wall. constrictive negative remodeling.

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In-stent Restenosis| Radcliffe Cardiology

In these videos, Consultant Interventional Cardiologists Dr Peter O’Kane and Dr Jehangir Din perform two cases, incorporating iFR and IVUS, highlighting the challenges and practical approaches to complex PCI with in-stent restenosis. Additionally, the physicians demonstrate AngioSculpt, iFR co-registration, and the use of laser.

Treatment strategies for in-stent restenosis in peripheral

INTRODUCTION. Advancements in endovascular stent technology have addressed limitations associated with conventional percutaneous transluminal balloon angioplasty in patients with chronic peripheral arterial disease (PAD) of the lower limbs, such as elastic recoil, residual stenosis and flow-limiting dissection [].However, a considerable proportion of patients with PAD treated with stenting

Nearly 10% of PCIs performed for in-stent restenosis

For patients who underwent in-stent restenosis PCI, the rate of patients with bare-metal stent in-stent restenosis declined from the third quarter of 2009 to the second quarter of 2017 (2.6% to 0

Drug-Eluting Balloon for In-Stent Restenosis – American

A Randomized Comparison of Paclitaxel-eluting Balloon Versus Everolimus-eluting Stent for the Treatment of Any In-stent Restenosis: The DARE Trial. JACC Cardiovasc Interv 2017;Oct 30:[Epub ahead of print]. Presented by Dr. Jose P.S. Henriques at the Transcatheter Cardiovascular Therapeutics meeting (TCT 2017), Denver, CO, .

Angiographic Patterns of In-Stent Restenosis | Circulation

In-stent restenosis lesion length was measured from number of seconds on videotape. At a pullback speed of 0.5 mm/s, 2 s of videotape playback equals 1 mm of axial stent length. This has been validated in vivo. 15 In-stent restenosis length was defined as the axial length of a stented or nonstented segment

PDF Treatment strategies for coronary in-stent restenosis

of coronary in-stent restenosis and the need for target lesion revascularisation compared with bare metal stents by counteracting the exuberant neointimal pro-liferation that follows stent implantation.1 However, current rates of in-stent restenosis in clinical practice remain higher than 10%. 2 3 Management of patients with in-stent restenosis is

Is a bare-metal stent still useful for improving the

Among the patients treated by BMS, the cut-off lesion reference for the development of in-stent restenosis (ISR) was calculated by comparing patients with and without ISR. In all patients with a lesion reference above/below the cut-off point of BMS-ISR, medium-term clinical and angiographic outcomes were compared between the BMS and DES groups.

Waksman In-Stent Restenosis Classification: A Mechanism

The Waksman In-Stent Restenosis Classification has been recently introduced to identify ISR based on disease processes (Table 1) [15]. Intravascular imaging data have demonstrated that ISR lesion morphology is related to future events, and optimization of treatment of restenosis is essential [16].

Patterns and Mechanisms of In-Stent Restenosis | Circulation

Although Palmaz-Schatz stent placement has been shown to reduce the rate of restenosis compared with balloon angioplasty, 1 2 in-stent restenosis is a significant and (with increased stent implantation in intervention cardiology) a growing clinical problem. Recent histological and angiographic studies have suggested that stents trigger the development of neointimal hyperplasia, whereas other

Treatment of Coronary In-Stent Restenosis with a

The incidence of in-stent restenosis after percutaneous coronary intervention ranges from 5 to 35% after the implantation of an uncoated stent and is somewhat lower after the implantation of a

Incidence and Risk Factors of In-Stent Restenosis for

BACKGROUND: In-stent restenosis affects long-term outcome in patients with intracranial atherosclerotic stenosis. PURPOSE: The aim of this meta-analysis was to evaluate the incidence and risk factors of in-stent restenosis. DATA SOURCES: All literature that reported in-stent restenosis was searched on PubMed, Ovid EMBASE and Ovid MEDLINE data bases.

Mechanism of edge restenosis after drug-eluting stent

Binary restenosis occurred in 161 lesions in 119 patients. We retrospectively compared the 3 DES with regard to the percentage of edge stent restenosis among all cases of restenosis. We also evaluated the maximal, minimal, and Δ (maximal angle-minimal angle) angles. The percentage of edge restenosis was higher for SES than for ZES (37.5% vs

Folate Therapy and In-Stent Restenosis after Coronary

Exclusion criteria were in-stent restenosis, significant left-main-artery stenosis and bifurcation lesions, myocardial infarction less than 24 hours before enrollment, renal dysfunction (defined

Coronary In-Stent Restenosis: Assessment with CT Coronary

Purpose To compare accuracy and radiation exposure of a new computed tomographic (CT) scanner with improved spatial resolution (scanner A) with those of a CT scanner with standard spatial resolution (scanner B) for evaluation of coronary in-stent restenosis (ISR) by using invasive coronary angiography (ICA) and intravascular ultrasonography (US) as reference methods. Materials and Methods

Slight Advantage for DES Over DCB for In-Stent Restenosis

. Angiographic outcomes are slightly worse with drug-coated balloons (DCB) than with second-generation DES for treating in-stent restenosis, an updated meta-analysis confirms. But experts say there are times when the benefits of DCB outweigh that disadvantage. Pooling results from seven trials, investigators led by Islam Elgendy

Recurrent Drug-Eluting Stent In-Stent Restenosis: A State

Introduction. In-stent restenosis is a corollary of the improved durability of modern-day coronary interventions. This was a striking limitation of bare metal stents (BMS) resulting from gradual intimal and medial hyperproliferation within the stented segment, usually occurring in the first year of intervention.

In-stent Restenosis | SpringerLink

In 1998, 539,000 percutaneous transluminal coronary angioplasty (PTCA) procedures were performed in the United States, an increase of 248% since 1987 [1]. Most of these interventions were followed by stenting. The advent of stents has revolutionized interventional cardiology; however, the Achilles’ heel of stenting is in-stent restenosis (ISR).

US In-Stent Restenosis Rates Show No Signs of Budging

Among 5.1 million percutaneous coronary interventions (PCIs) performed in the United States, 1 in 10 were performed for in-stent restenosis (ISR). Rates ticked up slightly over the study period

Successful Management of Coronary In-Stent Restenosis: A

In-stent restenosis (ISR) is identified on coronary vessel angiography. It is defined as a ≥50% stenosis of the coronary vessel diameter at the stent segment or its edges (5-mm segments adjacent upstream and downstream to the stent) .The incidence of ISR with a bare-metal stent (BMS) is higher when compared with a drug-eluting stent (DES).

Clinical outcomes of rotational atherectomy in severely

INTRODUCTION. In-stent restenosis (ISR) remains a challenging issue of percutaneous coronary intervention (PCI) even in the drug-eluting stent era. 1 Several techniques, including balloon angioplasty, plaque debulking, vascular brachytherapy, additional stent implantation, and use of a drug-coated balloon have been performed for the treatment of ISR, and the implantation of a new-generation

Absorb BRS for in-stent restenosis: the final bow before

Restenosis in drug-eluting stents (DES) complicates 3%-8% of procedures at 1 year, 8%-15% at 2 years and 8%-31% at 10 years. 1 2 Restenosis after plain-old balloon angioplasty (POBA) is due to negative remodelling, while restenosis after bare metal stent (BMS) is mostly related to neointimal hyperplasia. However, restenosis after DES is due to the combination of neointimal hyperplasia

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Coronary In-Stent Restenosis: Assessment with Corrected

Introduction. Stent implantation is a mainstay in the treatment of significant coronary artery disease. With the increasing use of drug-eluting stents, the occurrence of in-stent restenosis (ISR) has decreased (1,2).Nonetheless, ISR occurs in about 4%-10% of patients who present with recurrent chest pain (3,4).Coronary computed tomographic (CT) angiography has emerged as a reliable tool for

Understanding and managing in-stent restenosis: a review

In-stent restenosis (ISR) has always been considered the “enemy” for the interventional cardiologists, thus many technical improvements in the last 20 years aimed at reducing its occurrence: firstly, newer generation bare metal stents (BMS) , then drug-eluting stents (DES) and finally drug-coated balloons (DCB) (5,6).

In stent restenosis – SlideShare

In stent restenosis. 1. In-Stent restenosis Dr. Sahar Gamal El-Din National Heart Institute. 2. DEFINITION • ISR is defined as the gradual re-narrowing of a stented coronary artery lesion due to arterial damage with subsequent neointimal tissue proliferation. • Angiographically IRS is defined as recurrent diameter stenosis at the stent

Frontiers | Treatment of the Carotid In-stent Restenosis

Background and Purpose: In-stent restenosis (ISR) after carotid artery stent (CAS) is not uncommon. We aimed to evaluate therapeutic options for ISR after CAS.Methods: We searched PubMed and EMBASE until November 2, 2020 for studies including the treatment for ISR after CAS.Results: In total, 35 studies, covering 1,374 procedures in 1,359 patients, were included in this review.

New recipes for in-stent restenosis: cut, grate, roast, or

In-stent restenosis is set to become a large part of our interventional practice in the new millennium. Stent implantation has grown so much that it now comprises 60-70% of all percutaneous coronary revascularisation interventions, and assuming a conservative 25% restenosis rate for a total of around one million percutaneous transluminal coronary angioplasty (PTCA) procedures this year, more

Coronary In-Stent Restenosis: Predictors and Treatment (24

In-stent restenosis (ISR) is characterized by progressive narrowing of a coronary lesion previously treated with a stent (1). ISR is a result of stent-induced mechanical injury to the arterial

In-Stent Restenosis — Cardiology Patients' Forum

“In-stent restenosis is the bane of coronary angioplasty, and drug-eluting balloon angioplasty is a promising treatment option in this situation. It reduces the risk for MACE compared with plain balloon angioplasty or implantation of a Taxus Liberte drug-eluting stent.” Angioplasty.Org Staff, Angioplasty.Org,

Treatment of Coronary In-Stent Restenosis – Full Text View

In-stent restenosis after coronary angioplasty is currently one of the main limitations of this method, leading to a recurrence of exertional angina pectoris or manifesting as acute coronary syndrome. Histopathologic substrate of in-stent restenosis is neointimal hyperplasia.

In-Stent Restenosis and a Drug-Coated Balloon: Insights

In-stent restenosis may lead to the recurrence of major cardiovascular adverse events, including angina pectoris, acute myocardial infarction, and even sudden cardiac death. These events are currently serious problems that occur after coronary stent implantation. Clinical physicians face a difficult choice for in-stent restenosis treatment.

Imaging challenges of carotid artery in-stent restenosis

Internal carotid artery stenosis is an established risk factor for stroke. Therefore, carotid artery revascularization has an important role in the prevention and treatment of stroke. For the treatment of carotid artery stenosis, carotid artery stenting (CAS) has currently gained acceptance as a safe alternative to carotid endarterectomy (CEA), particularly in patients at high surgical risk.

Oral Sirolimus for In-Stent Restenosis – Full Text View

Randomized, double-blind, placebo-controlled trial of oral sirolimus for restenosis prevention in patients with in-stent restenosis: the Oral Sirolimus to Inhibit Recurrent In-stent Stenosis (OSIRIS) trial. Circulation. 2004 Aug 17;110(7):790-5. Epub 2004 Aug 9.

In-Stent Restenosis: Pathophysiology and Treatment

Management of in-stent restenosis (ISR) remains a clinical challenge after both bare metal stent and drug-eluting stent placement. Autopsy studies and intravascular imaging have augmented our understanding of the pathophysiology of ISR. The clinical presentation and symptoms vary considerably among patients from stable angina to unstable angina and acute myocardial infarction. Potential

Impact of anemia on in-stent restenosis after percutaneous

Anemia is a common risk factor for post-percutaneous coronary intervention (PCI) adverse events; however, data on its association with in-stent restenosis (ISR) is limited. 538 patients who underwent PCI between January 2017 and September 2019 and follow-up angiography 9-12 months after the initial PCI were enrolled in this study.

Drug-eluting balloons versus new generation drug-eluting

Background: New-generation drug-eluting stents (DES) was more effective in the treatment of in-stent restenosis (ISR) compared with the first-generation DES. Drug-eluting balloons (DEB) and new-generation DES had been available strategies in treatment of bare-metal stents/DES ISR (BMS/DES-ISR).

Diabetes and restenosis | Cardiovascular Diabetology

Restenosis, defined as the re-narrowing of an arterial lumen after revascularization, represents an increasingly important issue in clinical practice. Indeed, as the number of stent placements has risen to an estimate that exceeds 3 million annually worldwide, revascularization procedures have become much more common. Several investigators have demonstrated that vessels in patients with

Paclitaxel Coated Balloon vs. Bare Metal Stent for

Background: Stenting treatment for refractory symptomatic patients with vertebral artery origin stenosis (VAOS) is safe; however, there is a high rate of in-stent restenosis. Although drug-eluting stents can reduce the incidence of restenosis to some extent, there is still a risk caused by stent fracture.

Percutaneous Coronary Intervention for In-Stent Restenosis

In-stent restenosis more likely occurred in patients with diabetes, and the rate of complication due to diabetes mellitus might be higher among patients who underwent ISR CTO than those who underwent de novo CTO procedures. 11,14 However, this result was not observed in our study. In the present study, all patients who underwent ISR CTO PCI

Risk Factors for Recurrent Carotid-Artery Stenosis

Oszkinis et al. found that the incidence of restenosis following carotid interventions was up to 9.3% in a study including 16 patients underwent endovascular procedure. Sadideen et al. reported the restenosis rate reached as high as 37% . So far, few studies have focused on the recurrent stenosis after carotid artery stenting [9,10]. Thus, in

(PDF) Coronary restenosis: mechanisms, diagnosis and

In-stent restenosis spared the region mellitus, especially insulin-dependent, chronic renal failure of the carina, with stents presenting strut endothelialization under dialysis, and clinically unstable individuals. Angio- with no pattern of restenosis (lower left corner). 2 J Transcat Intervent. 2019;27:1-9 Journal of Coronary restenosis

Risk factors for in-stent restenosis after vertebral

title = “Risk factors for in-stent restenosis after vertebral ostium stenting”, abstract = “Purpose: To determine whether vascular risk factors, underlying vessel diameter, and/or the type of stent affect restenosis rates for vertebral ostium stents. Methods: A single-center retrospective analysis was conducted of 44 patients (31 men; mean age

Uncertainty quantification of a three-dimensional in-stent

2. In-stent restenosis three-dimensional model. ISR3D is a multiscale computational model simulating the post-stenting neointima growth in a coronary artery [12,13].It mainly consists of thr